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U.S. Highway 278 Route of US 278 in South Carolina highlighted in red Route information Auxiliary route of US 78 Maintained by SCDOT Length 146.130 mi (235.173 km) Existed 1965 –present Tourist routes Hilton Head Scenic Byway Major junctions West end US 1 US 78 / US 278 / SR 10 / SR 121 at the Georgia state line near North Augusta Major intersections US 25 / SC 121 in North Augusta I-520 in ...
U.S. Route 321 US 321 highlighted in red Route information Auxiliary route of US 21 Length 516.9 mi (831.9 km) Existed 1931–present Tourist routes Western York Scenic Byway Major junctions South end US 17 in Hardeeville, SC Major intersections I-26 in Cayce, SC I-20 in Columbia, SC I-85 in Gastonia, NC I-40 in Hickory, NC I-26 US 23 in Johnson City, TN I-40 in Newport, TN I-75 in Lenoir City ...
U.S. Highway 1 ( US 1) is a 170.540-mile (274.458 km) north–south U.S. Highway that crosses South Carolina from southwest to northeast and connects the cities of North Augusta, Aiken, Lexington, Columbia, Camden, and Cheraw . The route parallels Interstate 20 (I-20) closely from the Georgia border to Camden, where I-20 turns to a more ...
South Carolina Highway 41 Alternate ( SC 41 Alt.) is a 22.904-mile (36.860 km) alternate route that exists west of the SC 41 mainline path. It connects Centenary and Fork, via Marion, while the mainline travels through Mullins in this area. Established in 1951 or 1952 as a new alternate route of SC 41 through Marion, though it did replace part ...
Three miles (4.8 km) outside Anderson, US 29 Business (US 29 Bus.) takes a left turn and more direct route into the downtown area; while mainline US 29 continues east, with most signage signed "Truck" instead of the more usual "Bypass" (state maps confirm it is the mainline route). At South Carolina Highway 81 (SC 81), US 29 takes a left turn ...
South Carolina Highway 28 Route information Maintained by SCDOT Length 131.220 mi (211.178 km) Existed 1922 –present Tourist routes Savannah River Scenic Byway Northwestern segment Length 129.560 mi (208.507 km) West end SR 28 at the Georgia line near Pine Mountain, GA Major intersections US 123 from Seneca to Clemson US 76 from Seneca to Anderson I-85 near Anderson US 29 SC 24 / SC 81 in ...
U.S. Route 21 or U.S. Highway 21 (US 21) is a major north–south United States Numbered Highway in the Southeastern United States that extends 394 miles (634 km). The southern terminus is in Hunting Island State Park, South Carolina, 14.4 miles (23.2 km) south of the junction with US 21 Business (US 21 Bus.) and South Carolina Highway 802 (SC 802) in Beaufort.
U.S. Highway 17 ( US 17) is a 221.454-mile (356.396 km) north–south United States Numbered Highway in the U.S. state of South Carolina located near the Atlantic Ocean. The highway enters the state from Georgia at the Savannah River and serves Hardeeville, Charleston, Georgetown, and Myrtle Beach, before entering North Carolina near Calabash .
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