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Akt/PKB signaling pathway. The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals. Key proteins involved are PI3K ( phosphatidylinositol 3-kinase) and Akt ( protein kinase B ). Initial stimulation by one of the growth factors causes ...
Crystal structure of Akt-2-inhibitor complexes. [2] Protein kinase B ( PKB ), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration .
ac·ro·nym (ăk ′ rə-nĭm′) n. 1. A word formed by combining the initial letters of a multipart name, such as NATO from N orth A tlantic T reaty O rganization or by combining the initial letters or parts of a series of words, such as radar from ra dio d etecting a nd r anging.
Printed circuit board of a DVD player. Part of a 1984 Sinclair ZX Spectrum computer board, a printed circuit board, showing the conductive traces, the through-hole paths to the other surface, and some electronic components mounted using through-hole mounting. A printed circuit board ( PCB ), also called printed wiring board ( PWB ), is a medium ...
according to International Monetary Fund estimates [n 1] [1] Countries by nominal GDP in 2019 [n 2] > $20 trillion. $10–20 trillion. $5–10 trillion. $1–5 trillion. $750 billion – $1 trillion. $500–750 billion. $250–500 billion.
The PK ( Russian: Пулемёт Калашникова, transliterated as Pulemyot Kalashnikova, or "Kalashnikov's machine gun") [4] is a belt-fed general-purpose machine gun, chambered for the 7.62×54mmR rimmed cartridge. Designed in the Soviet Union and currently in production in Russia, [1] the original PK machine gun was introduced in ...
PRKACB. cAMP-dependent protein kinase catalytic subunit beta is an enzyme that in humans is encoded by the PRKACB gene. [5] cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the protein kinase A (PKA), which transduces the signal through phosphorylation of different target proteins.
Transcription factor II D ( TFIID) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. RNA polymerase II holoenzyme is a form of eukaryotic RNA polymerase II that is recruited to the promoters of protein -coding genes in living cells. It consists of RNA polymerase II, a subset of general ...