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JAK-STAT signaling pathway. The JAK-STAT signaling pathway is a chain of interactions between proteins in a cell, and is involved in processes such as immunity, cell division, cell death, and tumour formation. The pathway communicates information from chemical signals outside of a cell to the cell nucleus, resulting in the activation of genes ...
STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT3 is phosphorylated by receptor-associated Janus kinases (JAK), forms homo- or heterodimers, and translocates to the cell nucleus where it acts as a transcription activator. Specifically, STAT3 becomes activated after phosphorylation of tyrosine 705 ...
Qlucore Omics Explorer – interactive and visual data analysis software. RapidMiner – machine learning toolbox. Regression Analysis of Time Series (RATS) – comprehensive econometric analysis package. Rguroo Statistical Software - An online statistical software designed for teaching and analyzing data.
Jacob Cohen (April 20, 1923 – January 20, 1998) was an American psychologist and statistician best known for his work on statistical power and effect size, which helped to lay foundations for current statistical meta-analysis [1][2] and the methods of estimation statistics. He gave his name to such measures as Cohen's kappa, Cohen's d, and ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 17 September 2024. Observation that in many real-life datasets, the leading digit is likely to be small Not to be confused with the unrelated adage Benford's law of controversy. The distribution of first digits, according to Benford's law. Each bar represents a digit, and the height of the bar is the ...
Primer (molecular biology) The DNA replication fork. RNA primer labeled at top. A primer is a short, single-stranded nucleic acid used by all living organisms in the initiation of DNA synthesis. A synthetic primer may also be referred to as an oligo, short for oligonucleotide. DNA polymerase (responsible for DNA replication) enzymes are only ...
STAT6. Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that belongs to the Signal Transducer and Activator of Transcription (STAT) family of proteins. [5] The proteins of STAT family transmit signals from a receptor complex to the nucleus and activate gene expression.
Members of the signal transducer and activator of transcription (STAT) protein family are intracellular transcription factors that mediate many aspects of cellular immunity, proliferation, apoptosis and differentiation. They are primarily activated by membrane receptor-associated Janus kinases (JAK). Dysregulation of this pathway is frequently ...