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Entrez Global Query is an integrated search and retrieval system that provides access to all databases simultaneously with a single query string and user interface. Entrez can efficiently retrieve related sequences, structures, and references. The Entrez system can provide views of gene and protein sequences and chromosome maps. Some textbooks are also available online through the Entrez system.
The archive was established by the National Center for Biotechnology Information (NCBI) in 2007 in order to provide a repository for data produced by RNA-Seq and ChIP-Seq studies as well as large-scale studies including the Human Microbiome Project and the 1000 Genomes Project. [1] [2] Originally called the Short Read Archive, the name was changed in anticipation of future sequencing ...
The goal of the NCBI conserved domain curation project is to provide database users with insights into how patterns of residue conservation and divergence in a family relate to functional properties, and to provide useful links to more detailed information that may help to understand those sequence/structure/function relationships. To do this, CDD Curators include the following types of ...
Expressed sequence tag. In genetics, an expressed sequence tag ( EST) is a short sub-sequence of a cDNA sequence. [1] ESTs may be used to identify gene transcripts, and were instrumental in gene discovery and in gene-sequence determination. [2]
PubChem is a database of chemical molecules and their activities against biological assays. The system is maintained by the National Center for Biotechnology Information (NCBI), a component of the National Library of Medicine, which is part of the United States National Institutes of Health (NIH). PubChem can be accessed for free through a web ...
The genome browser is an important tool for studying the genome. In bioinformatics, a genome browser is a graphical interface for displaying information from a biological database for genomic data. [2] It is a software tool that displays genetic data in graphical form. Genome browsers enable users to visualize and browse entire genomes with ...
FASTA format. In bioinformatics and biochemistry, the FASTA format is a text-based format for representing either nucleotide sequences or amino acid (protein) sequences, in which nucleotides or amino acids are represented using single-letter codes.
The primary resources for the content of the Epigenomics Database are derived from two archival databases at the NCBI: The Gene Expression Omnibus (GEO) and the Sequence Read Archive (SRA). [1] The Gene Expression Omnibus is a data system for high-throughput genomic data that is generated from microarray and next-generation sequencing technologies. [3] Data used in the Epigenomics database is ...